Changes in the concept of acute DVT treatment

Deep venous thrombosis (DVT) of the lower limbs is a common disease caused by blood clotting in the deep veins of the lower limbs and blocking the lumen, resulting in a series of clinical symptoms. DVT is the third largest vascular disease after cerebrovascular and coronary artery diseases, and its incidence rate is increasing year by year. DVT includes a series of pathophysiological processes, and some patients can develop pulmonary embolism, deep vein thrombosis syndrome, and eventually lead to disability or death. In particular, DVT patients who attack in the hospital are often combined with or secondary to other diseases, such as orthopedic joint replacement, multiple trauma, spine or neurosurgery, obstetrics and Gynecology, oncology, internal medicine chronic diseases, etc., which are filled in almost every ward of the general hospital and have the characteristics of hidden onset, 80% of the patients have no clinical symptoms in the early stage, and sudden death often occurs if the diagnosis and treatment are not timely. In the later stage, they are not only prone to recurrence but also have high long-term complications. Among them, the recurrence rate of VTE in 5 years is 24.3%, and the recurrence rate of VTE in 8 years is 29.7%. The incidence rate of post thrombotic syndrome (PTS) can reach more than 65%. Chronic pulmonary hypertension (CTEPH) also has a high incidence, The treatment cost is high, which brings heavy economic burden to patients. Therefore, how to better prevent and treat DVT has been a widespread concern of clinicians. In recent years, new oral anticoagulants have been developed and widely used, the products of inferior vena cava filters have been continuously improved, the clinical application has been mature and standardized, the thrombolytic catheters and mechanical dynamic thrombus removal devices have been widely used, and the treatment concept of DVT has gradually changed. In the past 20 years, it can be said that it has gone through four stages: attaching importance to symptom treatment, controlling thrombus spread, attaching importance to thrombus removal and attaching importance to the elimination of etiology.

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Post time: Sep-19-2022